One of the most striking signs of aging is the increase of wrinkles on the face. This can occur naturally over time and is identified by certain biochemical, histological, and physiological changes that are amplified by environmental exposure and other secondary factors such as the pull of gravity or repeated facial movement caused by the contraction of muscles of facial expression. Muscles are contracted when the vesicle in the motor neuron releases a neurotransmitter.

Hexapeptide mimics the N-terminal end of SNAP25- and it competes with the natural protein for a position in the SNARE complex. If the SNARE complex is slightly destabilized, the vesicle cannot release neurotransmitter efficiently and therefore muscle contraction is attenuated, preventing the formation of lines and wrinkles.